![]() The fluorine moiety protects the drug from isoenzyme inactivation in the kidney, allowing it to exert its mineralocorticoid effect. Fludrocortisone is a fluorinated analog of cortisone. The outer zona glomerulosa secretes mineralocorticoids Mineralocorticoids Mineralocorticoids are a drug class within the corticosteroid family and fludrocortisone is the primary medication within this class. ![]() The outer parenchyma is called the adrenal cortex and has 3 distinct zones, each with its own secretory products. ![]() As part of the urinary tract, the kidneys are responsible for blood filtration and excretion of water-soluble waste in the urine. Glandular Epithelium: Histology located above the kidneys Kidneys The kidneys are a pair of bean-shaped organs located retroperitoneally against the posterior wall of the abdomen on either side of the spine. These hormones influence the metabolism and other functions of cells in the body. ![]() The adrenal glands are a pair of retroperitoneal Retroperitoneal Peritoneum: Anatomy endocrine glands Endocrine glands Ductless glands that secrete hormones directly into the blood circulation.
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